Understanding implies abilities and dispositions with respect to an object. Both comprehension and understanding can be used to talk about someone's ability to understand something. Or about how something works:
Understanding the circular flow of and spending Artofit
Comprehension usually used with of. Understanding is a relation between the knower and an object of understanding. Understanding a concept means you get it.
The meaning of understanding is a mental grasp :
Knowledge about a subject, situation, etc. How to use understanding in a sentence. Your understanding might be that your mother will always drive you to school if you miss the bus. He noted bond's apparent lack of.